I have run into this issue on several occasions, usually when the server has experienced some kind of change or issue. This included a VMotion (in a virtual environment) that caused some issues, as well as a reboot after patching and some module updates. Normally I was logged into the server as myself, and when I tried to troubleshoot the issue as myself, I did not have success. I eventually discovered the problem, and then used it going forward on numerous occasions. We had set up a network account for our Orion environment, and the reports were set to run daily under this account. I logged onto the server using this account, and then opened up each report with the account and resaved it (and re-entered the credentials upon saving). To test, I then ran each report for delivery immediately and verified, since I had myself as a recipient on each report to make sure they ran daily. It was almost like I had to reapply the credentials occasionally.
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