We use something like this SQL Query to programmatically turn off pollers we do not want to use. We flag devices to apply this script against based on their membership in a group that uses a dynamic query. You could use this to do the opposite I think. However, if the node/pollers have not been discovered yet then you will have to work with the discovered nodes. I am just beginning to look at the schema for the discovery tables, so if you have gain insights into how they work, please post. thanks
UPDATE Pollers SET Enabled = 0
WHERE (NetObjectType = 'N') AND
(PollerType LIKE '%Routing%'
OR PollerType LIKE '%Topology%'
OR PollerType LIKE '%VRFRouting%')
AND (Enabled = 1)
AND
(EXISTS (SELECT S.EntityID
FROM [ContainerMemberSnapshots] S
JOIN [Containers] C ON S.ContainerID = C.ContainerID
WHERE S.EntityDisplayName = 'Node' AND C.IsDeleted = '0' AND S.ContainerID = '8'))
AND
(NetObjectID IN (SELECT S.EntityID
FROM [ContainerMemberSnapshots] S
JOIN [Containers] C ON S.ContainerID = C.ContainerID
WHERE S.EntityDisplayName = 'Node' AND C.IsDeleted = '0' AND S.ContainerID = '8'))
